A 9-year-old, female-neutered West Highland White Terrier presented with a left forelimb lameness and maxillary oral mass. Radiography revealed a large, extensive aggressive bone lesion in the distal radius. CT scan revealed a large invasive oral mass and widespread skeletal osteolysis. Cytology and histology samples confirmed multiple myeloma. Haematology and biochemistry revealed no typical changes, including an absence of hyperglobulinaemia. There was no monoclonal gammopathy detected on protein electrophoresis.
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