A two-year-old, neutered male, old English sheepdog was presented for further investigation of generalised tonic-clonic seizures. MRI of the brain revealed cortical grey matter thickening, grey-white matter blurring and malformation of the prorean and precruciate gyrus and absence of the presylvian sulcus. These findings are consistent with congenital focal cortical dysplasia; although the histopathological findings have been previously described in dogs, the MRI findings have not yet been reported in the veterinary literature. Phenobarbitone was added at the time of diagnosis with levetiracetam being added after 12 months due to worsening seizure frequency. Cortical dysplasia, although uncommon, should be considered as a differential diagnosis in an adult dog with generalised seizures.
- cortical dysplasia
- Received October 7, 2015.
- Revision received October 27, 2015.
- Accepted November 1, 2015.
- British Veterinary Association
Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.