An 11-year-old female Chinese crocodile lizard (Shinisaurus crocodilurus) with presumed seizures was examined. Complete blood count, plasma biochemistry and MRI did not identify a cause of seizures and thus cryptogenic epilepsy was diagnosed. Electroencephalogram (EEG) was performed on the affected lizard and a healthy conspecific, revealing a lack of normal background electrical activity in the affected individual compared with the normal individual. The patient was treated with oral phenobarbital and serum phenobarbital levels were routinely measured. Although phenobarbital was an effective antiepileptic drug, the patient's clinical condition worsened and the lizard was humanely euthanased after 70 days of therapy. Postmortem examination and histopathology did not identify a cause for the seizures. This is the first description of seizures, MRI, EEG and seizure treatment in a Chinese crocodile lizard.
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Contributors SB was the primary clinician during initial treatment of this case and was the primary author of the paper. TH and RFW provided mentorship to SB and assumed responsibility for the case when SB was occupied with other duties. CW provided neurological expertise and performed the electroencephalogram. ME provided radiographic interpretation and MRI captions.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.
Data sharing statement No additional data are available.
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