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Dogs
Repeated arterial chemoembolisation in a dog with an unresectable hepatocellular carcinoma
  1. Joy Fenner1,
  2. Abby Caine2,
  3. Jon Wray1 and
  4. Simon Tappin1
  1. 1 Small Animal Internal Medicine, Dick White Referrals, Six Mile Bottom, Cambridgeshire, CB8 0UH, UK
  2. 2 Diagnostic Imaging, Dick White Referrals, Six Mile Bottom, Cambridgeshire, UK
  1. Correspondence to Simon Tappin; st{at}dwr.co.uk

Abstract

An 11-year-old male neutered Staffordshire bull terrier presented for investigation of inappetence and intermittent postprandial abdominal pain. An 8 cm diameter mass was documented within the right lateral lobe of the liver. An exploratory laparotomy was performed and removal attempted however the mass was unresectable. Biopsy confirmed a low-grade hepatocellular carcinoma. Arterial chemoembolisation was performed and the patient discharged three days later. The mass was documented to gradually reduce in size before slowly regrowing, then to remain stable until 10 months postchemoembolisation, when the patient again became inappetent. At this time the mass was 11.5 cm diameter. Repeat chemoembolisation was performed as previously. The patient developed pancreatitis following the procedure and remained hospitalised for 10 days. Five weeks after the second procedure, the mass had reduced to 8 cm in diameter. Signs of pancreatitis returned and the dog was euthanased nine weeks after the second procedure; 14 months after the first.

  • Liver
  • Chemotherapy
  • chemoembolization
  • Tumour
  • Received February 7, 2017.
  • Revision received May 25, 2017.
  • Accepted June 1, 2017.

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  • Received February 7, 2017.
  • Revision received May 25, 2017.
  • Accepted June 1, 2017.
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Footnotes

  • Contributors ST managed this case and was the primary clinician. JW and AC assisted with both procedures. JF reviewed case notes, collated images and wrote the first draft of this manuscript. All authors were involved in reviewing the final version, which has undergone numerous revisions.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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