Article Text

Mammals (other)
Tetralogy of Fallot in a red ruffed lemur (Varecia rubra)


A 3.5-month-old male 1.4 kg red ruffed lemur (Varecia rubra) was evaluated following auscultation of a grade IV/VI systolic cardiac murmur during routine neonatal examination. Echocardiography revealed a perimembranous ventricular septal defect (VSD), overriding (dextropositioned) aorta, right ventricular concentric hypertrophy and moderate pulmonic valve stenosis. There was right-to-left blood flow through the VSD. These findings are consistent with a tetralogy of Fallot with right-to-left shunting. Despite the poor prognosis associated with this disease, this patient has done relatively well for six years. To the authors’ knowledge, this is the first published report of a tetralogy of Fallot in any lemur species.

  • tetralogy of fallot
  • prosimian
  • red-ruffed lemur
  • congenital heart disease

Statistics from

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.