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MRI findings of diffuse polioencephalopathy secondary to ethylene glycol intoxication in a dog


A six-year-old, female spayed German shepherd dog presented with an acute onset of disorientation, lethargy, polydipsia, vomiting and one episode of seizure activity. MRI of the brain revealed diffuse contrast enhancement of meninges and the grey matter in the cerebral hemispheres and cerebellum on T1-weighted images. Abdominal ultrasonography showed bilateral renal changes. The dog deteriorated and was euthanised. On postmortem examination small oxalate crystals were identified in the kidneys, meningeal vessels and capillaries of the grey matter confirming ethylene glycol intoxication.

  • Magnetic resonance imaging (MRI)
  • Neurotoxicology
  • Dogs
  • Ultrasonography
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