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Exocrine pancreatic insufficiency with concurrent pancreatitis, inflammatory bowel disease and cholangiohepatitis in a cat
  1. Chiara Costa Devoti1,
  2. Kevin Murtagh2,
  3. Daniel Batchelor2 and
  4. Paolo Silvestrini2
  1. 1Small Animal Teaching Hospital, University of Liverpool, Liverpool, UK
  2. 2Department of Internal Medicine, Small Animal Teaching Hospital, University of Liverpool, Cheshire, UK
  1. Correspondence to Chiara Costa Devoti, chiaracostadevoti{at}


A five-year-old male Persian cat was referred for chronic weight loss, polyphagia and clay-coloured voluminous stools. Serum biochemistry showed elevated liver enzyme activity, hypocholesterolaemia and hypocobalaminaemia. On abdominal ultrasound, a thickened small intestinal wall and tortuous biliary tract were detected. Surgical biopsies of the small intestine, liver and pancreas with concurrently low serum trypsin-like immunoreactivity allowed a final diagnosis of pancreatitis, inflammatory bowel disease, cholangiohepatitis and exocrine pancreatic insufficiency. The cat was treated with antibiotics, prednisolone, oral pancreatic enzymes and parenteral cobalamin. At one-year follow-up, medical treatment has led to a complete resolution of clinical signs.

  • Pancreas
  • Cats
  • Insufficiency
  • Triaditis
  • Gastroenterology
  • Internal medicine
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