A five-year-old male Persian cat was referred for chronic weight loss, polyphagia and clay-coloured voluminous stools. Serum biochemistry showed elevated liver enzyme activity, hypocholesterolaemia and hypocobalaminaemia. On abdominal ultrasound, a thickened small intestinal wall and tortuous biliary tract were detected. Surgical biopsies of the small intestine, liver and pancreas with concurrently low serum trypsin-like immunoreactivity allowed a final diagnosis of pancreatitis, inflammatory bowel disease, cholangiohepatitis and exocrine pancreatic insufficiency. The cat was treated with antibiotics, prednisolone, oral pancreatic enzymes and parenteral cobalamin. At one-year follow-up, medical treatment has led to a complete resolution of clinical signs.
- Internal medicine
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