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Ischaemic neuromyopathy associated with systemic lupus erythematosus in cats


Three cats presented to the hospital with multisystemic signs including oral ulceration and bleeding, spontaneous subcutaneous haemorrhages, fever, lethargy, anorexia and renal disease. The cats, two male and one female, were all older than six years (mean age eight years). All three cats also had a chronic history of lameness in one thoracic limb, which had progressed to non-ambulatory paresis. Marked muscle atrophy was present over the entire limb. Palpation of the axilla revealed a prominent tender cord-like structure, which on postmortem examination was found to be the swollen brachial plexus in each cat. The diagnosis of systemic lupus erythematosus was based on clinical assessment and laboratory data. All had ischaemic neuromyopathy confirmed on histopathological examination. Prednisolone with chlorambucil and pentoxifylline was administered orally. Unfortunately, none of the cats survived more than seven weeks from diagnosis.

  • Cats
  • Neuropathology
  • Myopathy
  • Autoimmune disease
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