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MRI and clinical resolution of a suspected intracranial toxoplasma granuloma with medical treatment in a domestic short hair cat
  1. Abbe Harper Crawford,
  2. Randi Drees and
  3. Elsa Beltran
  1. Department of Clinical Science and Services, Royal Veterinary College, Hatfield, UK
  1. Correspondence to Dr Abbe Harper Crawford; ahcrawford{at}


A two-year-old cat was presented with a left paradoxical vestibular syndrome. MRI of the brain revealed an extra-axial homogenously contrast enhancing mass in the region of the left caudal cerebellar peduncle. Toxoplasma serology was consistent with active infection and the lesion was suspected to be a toxoplasma granuloma. Following eight weeks of tapering oral prednisolone and 11 weeks of oral clindamycin treatment, repeat MRI revealed resolution of the lesion. Eighteen months after initial diagnosis, the cat remained neurologically normal. Differential diagnoses for a solitary, extra-axial, contrast enhancing mass lesion in the feline brain should include toxoplasma granuloma, which can undergo MRI and clinical resolution with medical treatment.

  • Cerebellar granuloma
  • Paradoxical vestibular syndrome
  • Medical treatment
  • Toxoplasma
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  • Contributors All authors substantially contributed to the conception and design of the manuscript, the analysis and interpretation of the data, drafting the article and final approval of the version submitted for publication.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement No additional data are available.

  • Correction notice This paper has been amended since it was published Online First. Owing to a scripting error, some of the publisher names in the references were replaced with 'BMJ Publishing Group'. This only affected the full text version, not the PDF. We have since corrected these errors and the correct publishers have been inserted into the references.

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