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Diagnosis of Caroli syndrome in a crossbreed dog
  1. Gonçalo Serrano1,
  2. Femke Mortier1,
  3. Leslie Bosseler2,
  4. Olivia Taylor3 and
  5. Dominique Paepe1
  1. 1Department of Medicine and Clinical Biology of Small Animals, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
  2. 2Department of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
  3. 3Department of Medical Imaging of Domestic Animals and Orthopaedics of Small Animals, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
  1. Correspondence to Dr Gonçalo Serrano; goncalonserrano{at}


This case report describes Caroli syndrome in a young dog, which presented with fever, icterus, acute vomiting, weight loss, hyporexia and lethargy. Two days after hospital admission, the development of severe ascites prompted the use of abdominal CT, which revealed the presence of a thickened gall bladder wall with dilation of the intrahepatic and common bile ducts, intrahepatic bile duct sacculation, and acquired extrahepatic portosystemic shunts. Exploratory coeliotomy revealed a gall bladder mucocoele with tortuous bile ducts. The owners opted not to follow further treatment and elected for euthanasia. This case highlights an unusual cause of hepatic and posthepatic icterus, which should be included in the differential diagnosis list of a young dog presenting with icterus.

  • hepatic disease
  • imaging
  • liver
  • computed tomography (CT)
  • dogs
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  • Contributors GS, FM, LB, OT and DP produced the original draft of the manuscript. GS, FM and DP revised the manuscript. All authors read and approved the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement There are no additional data available for this paper.

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