Article Text

Download PDFPDF
Hypoadrenocorticism in two cats successfully treated with desoxycorticosterone pivalate
  1. Franziska Reimann,
  2. Stefanie Siol,
  3. Charlotte Schlüter and
  4. Reto Neiger
  1. Tierklinik Hofheim, Hofheim, Germany
  1. Correspondence to Professor Reto Neiger; reto.neiger{at}


Two cats were presented with lethargy and anorexia. Clinically, the cats showed hypothermia and dehydration. Blood examination in both cats showed hyponatraemia, hyperkalaemia and additionally azotaemia in case 1 and hypercalcaemia in case 2. In both cats, an adrenocorticotropic hormone (ACTH) stimulation test showed an insufficient stimulation of the adrenal glands. In case 1, markedly elevated endogenous ACTH was additionally measured. Both cats were successfully treated with a combination of desoxycorticosterone pivalate (DOCP) and prednisolone (0.15 mg/kg daily). Case 1 received a final concentration of 2.6 mg/kg DOCP every 30 days, while case 2 was successfully managed with 2.2 mg/kg every 28 days. These rare cases of feline hypoadrenocorticism demonstrate that DOCP can be used similarly as in dogs.

  • addison’s disease
  • feline
  • endocrinology
  • ACTH
  • cortisol
View Full Text

Statistics from


  • Contributors FF and SS jointly wrote manuscript, CS suprevised case 2 and RN supervised case 1 and helped to write manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement Data sharing is not applicable to this article as no datasets were generated or analysed during the current study.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.