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Digital trichoblastoma treated with electrochemotherapy in a dog
  1. Denner Santos Dos Anjos1,
  2. Ygor Amaral Rossi2,
  3. Larissa Fernandes Magalhães2,
  4. Sabryna Gouveia Calazans1 and
  5. Carlos Eduardo Fonseca-Alves3
  1. 1 Universidade Estadual Paulista Julio de Mesquita Filho Faculdade de Ciencias Agrarias e Veterinarias Campus de Jaboticabal, Jaboticabal, Brazil
  2. 2 Universidade de Franca, Franca, Brazil
  3. 3 Department of Veterinary Clinic, Universidade Paulista, Sao Paulo, Brazil
  1. Correspondence to Dr Denner Santos Dos Anjos; denner.anjosoncology{at}


Canine trichoblastoma is a benign tumour derived from the trichoblastic epithelium, commonly affecting the head and neck and, less commonly, the limbs and trunk. Herein, the authors report a case of a dog with digital trichoblastoma successfully treated with electrochemotherapy (ECT). The dog received three sessions of ECT with systemic bleomycin. The tumour volume decreased throughout the ECT sessions, with a complete response after 81 days. The patient presented a disease-free survival of 700 days. ECT may be a better approach than surgery for digital trichoblastomas because it avoids amputating the digit and provides a good cosmetic result.

  • electroporation
  • bleomycin
  • Dogs
  • basal cell carcinoma
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  • Contributors All authors contributed to the data collection, analysis of the data and writing of the manuscript. DA, YR and SC contributed to the management of the case, data collection and writing of the manuscript. LM and CFA evaluated the clinical pathology data and contributed to the writing of the manuscript. All authors reviewed the final version of this manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement No additional unpublished data was available because is included all available data in the

    original publication.

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