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Ectopic medullary (C cell) thyroid carcinoma in a dog with pericardial effusion
  1. Julie Hamilton-Elliott1,
  2. Riccardo Finotello1,
  3. Daniela Murgia2,
  4. Richard Blundell3 and
  5. Joanna Dukes-McEwan1
  1. 1 School of Veterinary Science, University of Liverpool Small Animal Teaching Hospital, Neston, UK
  2. 2 Surgery service, AHT, Newmarket, UK
  3. 3 Veterinary Pathology, The University of Liverpool, Neston, UK
  1. Correspondence to Julie Hamilton-Elliott; julieham{at}


A six-year-old, female, neutered crossbreed was presented to the University of Liverpool Small Animal Teaching Hospital for evaluation of pericardial effusion. Diagnostic imaging confirmed pericardial effusion and cardiac tamponade in addition to a mass located at the heart base. Thoracic CT revealed a strongly contrast-enhancing soft-tissue mass right lateral to the ascending aorta and ventral to the cranial vena cava with no evidence of metastatic disease. Subsequently, a subtotal pericardectomy was performed, and the mass was incompletely excised. Histopathology and immunohistochemistry revealed the mass to be an ectopic thyroid carcinoma of medullary (C cell) origin. The patient was treated with adjunctive chemotherapy (toceranib phosphate). Repeat staging two months later revealed no evidence of macroscopic tumour recurrence or metastatic disease. The patient was subsequently euthanased two months later due to complications of concurrent but unrelated hepatic disease.

  • cardiology
  • pericardial effusion
  • heart base mass
  • ectopic thyroid carcinoma
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  • Contributors JH-E was the primary clinician during treatment of the case and drafted the article for publication. RF, DM and RB provided critical revision of the article and contributed surgical and histopathological images to supplement the text. JD-M supervised the writing of the case report and revised the draft of the paper in addition to authorising final submission.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement No additional data are available.

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