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Cerebellar ischaemic infarct: a rare complication of pancreatitis
  1. Harriet Hall1,2,
  2. Ferran Valls Sànchez1,
  3. Anna Gardini3,
  4. Davide Corbetta2 and
  5. Jess Florey1
  1. 1Internal Medicine, Dick White Referrals, Six Mile Bottom, UK
  2. 2School of Veterinary Medicine and Science, University of Nottingham, Leicestershire, UK
  3. 3Neurology, Dick White Referrals, Six Mile Bottom, UK
  1. Correspondence to Harriet Hall; harrietrhall{at}


A 12-year-old female neutered Jack Russell terrier was presented for further investigation of an acute two-day history of lethargy, inappetence and vomiting. Mild increase in urea and amylase and positive cPLI (Canine pancreatic lipase immunoreactivity) ELISA were present. Abdominal ultrasound revealed an irregular, heterogeneous and diffusely hypoechoic pancreas. Severe pancreatitis with secondary peritonitis was diagnosed. Supportive treatment was started, but the patient developed paradoxical vestibular syndrome. MRI was declined and the patient was euthanased. On histopathological examination renal infarction with evidence of thrombosis and focal cerebellar infarction were present. It is well documented that a hypercoagulable state is a known complication of severe pancreatitis. To the authors’ knowledge this is the first description of suspected thromboembolism secondary to pancreatitis resulting in neurological signs in a dog.

  • dogs
  • central nervous system (cns)
  • brain diseases
  • haemostasis
  • pancreas
  • companion animals
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  • Contributors HRH, FVS, JF, AG of Dick White Referrals were all involved in writing the case report and the case management of this patient. JF was the supervising diplomat for this case. DC, resident and MVM postgraduate in Veterinary Anatomic Pathology at the University of Nottingham, contributed the pathology report for this case and the histology and postmortem images.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement No additional data are available.

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