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Dexmedetomidine infusion as perioperative adjuvant in a dog undergoing craniotomy
  1. Hamaseh Tayari and
  2. Andrew Bell
  1. School of Veterinary Medicine, University of Glasgow, Glasgow, UK
  1. Correspondence to Dr Hamaseh Tayari; h.tayari.1{at}


A 10-year-old castrated boxer with behavioural change due to a cerebellar meningioma was presented for intracranial surgery. As intracranial structures are virtually incompressible, any volume-occupying lesions such as meningiomas might raise intracranial pressure compromising cerebral perfusion. To avoid severe neuronal damage, maintaining and optimising the delicate balance between intracranial pressure and perfusion is mandatory. Dexmedetomidine, an α2-adrenoreceptor agonist, is gaining consensus in human neuroanaesthesia as an adjuvant in patients undergoing craniotomy. Unlike short-acting opioids, dexmedetomidine does not cause respiratory depression while having analgesic and neuroprotective properties; it provides a significant reduction of perioperative volatile anaesthetic and opioid requirements ensuring haemodynamic stability and smooth recoveries. Due to this dog’s aggressive behaviour and a shortage of remifentanil, dexmedetomidine infusion was chosen as part of the perioperative management of this patient.

  • anaesthesia
  • analgesia
  • dogs
  • craniotomy
  • meningioma
  • dexmedetomidine
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  • Contributors All authors made substantial contributions. HT: anaesthetic management of the case, preparation, writing the manuscript. AB: clinical supervision for the case and reviewed and approved the final version of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement No additional data are available.

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