This case report describes the clinical presentation, diagnosis and management of marked eosinophilic polysynovitis in a five-year-old male neutered kelpie dog. The dog was referred following a three-month history of multifocal lameness and intermittent fever that was unresponsive to NSAIDs or antibiotics. Marked eosinophilic inflammation of multiple joints was documented on synovial fluid analysis. No inciting agent was identified despite extensive diagnostic testing including serology for toxoplasmosis, antinuclear antibody, rheumatoid factor, heartworm antigen, urinalysis and faecal float. The dog responded well to immunosuppressive doses of prednisolone therapy, which was tapered and discontinued after eight months. Follow-up arthrocentesis revealed the eosinophilic polysynovitis had resolved.
- joint diseases
- immune-mediated diseases
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Contributors AB was involved in the clinical investigation and drafted and revised the case report. MC participated in the clinical investigation and revised the draft paper. EC performed the clinical pathology investigation, and provided images of the synovial fluid smears and assisted with drafting the paper. KJ was the senior veterinarian involved in the clinical investigation and revised the draft paper. All authors have read and approved the final paper.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.
Data sharing statement All data relevant to the study are included in the article or uploaded as supplementary information.
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