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Intradural-extramedullary osteosarcoma in a dog
  1. Giuseppe Bonanno1,
  2. Sergio Andrade Gomes,
  3. Sandra Dawson2,
  4. Joyce Bass3 and
  5. Mark Lowrie1
  1. 1 Dovecote Veterinary Hospital, Castle Donington, Derby, UK
  2. 2 NationWide Laboratories, Lancashire, UK
  3. 3 Finn Pathologists, Diss, UK
  1. Correspondence to Dr Mark Lowrie; mark.lowrie{at}


An 11-year-old male crossbreed dog was referred for progressive left forelimb lameness and proprioceptive deficits over four weeks. Neurolocalisation was consistent with a cervical lesion affecting the C1–C5 spinal segments. CT revealed a hyperattenuating lesion within the vertebral column. MRI revealed a suspected intradural-extramedullary, oval-shaped lesion displacing the spinal parenchyma. Surgical exploration confirmed this was an intradural lesion and so a durotomy was performed to remove the mass. The histopathological diagnosis was an extradural osteosarcoma. Chemotherapy was commenced and despite initial improvement, euthanasia was performed following acute deterioration two months later.

This is the first report of an extraskeletal and intradural-extramedullary spinal osteosarcoma in a dog. Extraskeletal osteosarcoma should be included as a differential diagnosis for an intradural-extramedullary lesion in dogs, particularly in the presence of suspected mineralised material on advanced imaging. As reported in human medicine, prognosis appears to be grave in dogs.

  • canine
  • extraskeletal osteosarcoma
  • spinal cord
  • cervical
  • neoplasia
  • calcification
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  • Contributors All coauthors have substantial contributions to the conception or design of the work, or the acquisition, analysis or interpretation of data; drafting the work or revising it critically for important intellectual content; and final approval of the version published. All authors agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement No additional data are available.

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