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Dogs
Electrochemotherapy as treatment for generalised squamous cell carcinoma in a dog
  1. Ana Maria Boncea1,2,
  2. Anca Cristea3 and
  3. Patrick Bourdeau1
  1. 1 Dermatology, Parasitology, Mycology Unit, Nantes Atlantic College of Veterinary Medicine, Food Science and Engineering, Nantes, France
  2. 2 Vet Derm Therapy, Bucharest, Romania
  3. 3 Vet Medical Center, Bucharest, Romania
  1. Correspondence to Dr Ana Maria Boncea; bonceaana{at}gmail.com

Abstract

Canine squamous cell carcinoma (cSCC) is the second most common cutaneous neoplasm in dogs. Treatment options are limited. Electrochemotherapy (ECT) has been proposed as an alternative treatment for many types of tumours. To describe the use of ECT as treatment for generalised cSCC. An adult dog (four years old) was diagnosed with generalised cSCC. There were 24 tumours with the size range of 0.3–3 cm. The biopsy revealed an infiltrate rich in epithelial squamous cells, associated with pyogranulomatous inflammation. ECT was elected as treatment of choice. Cisplatin was injected intratumorously. After five minutes, the electric pulses were applied. The complete tumour regression was noted four weeks after. The dog was still in complete remission, 20 months later. This is the first case reporting a complete long-term remission using ECT for generalised cSCC.

  • electrochemotherapy
  • dogs
  • squamous cell carcinoma
  • electroporation
  • cisplatin
  • tumours
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Footnotes

  • Contributors AMB (the corresponding author) is the first author and the writer of the manuscript. AC is the performer of ECT technique and the writer of the paragraph describing this technique. PB made the final critique before submission.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement No additional data are available.

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