Article Text

Download PDFPDF
Dogs
Magnetic resonance findings in a Cavalier King Charles spaniel with osteopetrosis, Chiari-like malformation and syringomyelia

Abstract

Osteopetrosis (OP) is a rare genetic condition characterised by osteoclast impairment, deficient bone remodelling and increased bone density. Human patients with OP often present with fractures, osteomyelitis, anaemia, abnormal skeletal development, cranial nerve compression and rarely increased intracranial pressure secondary to craniosynostosis and/or calvarial thickening. A 17-month-old male neutered Cavalier King Charles spaniel was presented for evaluation of occasional painful vocalisation. MR of the brain and the vertebral column revealed a rare association of Chiari-like malformation (CLM) and calvarial thickening due to diffuse OP resulting in severe cerebellar compression and herniation into the foramen magnum. To the authors’ knowledge, this report represents the first described case of calvarial thickening caused by OP in association with CLM and syringomyelia in veterinary medicine.

  • osteopetrosis
  • Chiari-like malformation
  • magnetic resonance imaging (MRI)
  • Cavalier King Charles spaniel
View Full Text

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.