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Osteosarcoma affecting multiple bones in a dog
  1. Eleanor Wyatt1,
  2. Martina Piviani1,
  3. Andrew F Rich2,
  4. Jeremy Raphael Mortier2,
  5. Eithne Comerford1 and
  6. Riccardo Finotello1
  1. 1Department of Small Animal Clinical Science, Institute of Veterinary Science, University of Liverpool, Neston, United Kingdom
  2. 2Department of Veterinary Pathology & Public Health, Institute of Veterinary Science, University of Liverpool, Neston, United Kingdom
  1. Correspondence to Dr Riccardo Finotello; rfinot{at}


A 9 years and 5 months old, neutered male, Rottweiler was presented for referral at the Small Animal Teaching Hospital, University of Liverpool, for investigations following a fracture of the left femur, which had occurred after minor trauma. Radiographs at the primary veterinary practice revealed a closed, slightly displaced, comminuted, proximal diaphyseal fracture, which had cortical thinning around the fracture site, suggestive of a pathological fracture. Advanced imaging (computed tomography) revealed polyostotic osteolytic lesions which contained contrast enhancing, soft tissue attenuating tissue, associated with cortical destruction throughout the appendicular and axial skeleton. Ultrasound-guided fine needle aspirates of four lesions (right scapular, right femoral, left pelvic and vertebral lesions) were assessed by a boarded clinical pathologist, confirmed diagnosis of a polyostotic osteosarcoma. The patient was euthanased and postmortem examination confirmed the diagnosis.

  • oncology
  • cytology
  • diagnostics
  • dogs
  • histopathology
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  • Contributors All authors listed on the manuscript, underneath the title, provided substantial contributions to the design of the manuscript and were involved in the acquisition of the data and its analysis. Each author was involved in critically appraising, providing figures for and revising their relevant section, as well as evaluating and advising on the final version.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement All data relevant to the study are included in the article.

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