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Malignant trigeminal nerve Schwannoma diagnosed via biopsy of the infraorbital nerve in a dog
  1. Matthew Green1,
  2. Marti Pumarola2,
  3. Mike Targett3,
  4. Shirley vanLelyveld1 and
  5. Mark Lowrie1
  1. 1Dovecote Veterinary Hospital, Derby, UK
  2. 2Department of Animal Medicine and Surgery, Universitat Autonoma de Barcelona, Bellaterra, Barcelona, Spain
  3. 3Department of Veterinary Medicine and Surgery, University of Nottingham, Loughborough, UK
  1. Correspondence to Dr Mark Lowrie; mark.lowrie{at}


A 12-year old, female neutered English Pointer presented with right-sided temporalis muscle atrophy and facial irritation over 2 weeks. Neurolocalisation was consistent with a right trigeminal neuropathy. MRI revealed a severely enlarged trigeminal nerve with involvement of the infraorbital nerve, which was palpable as a firm swelling over the maxilla. Incisional biopsy of the infraorbital nerve was performed and histopathological diagnosis was a malignant Schwannoma. Palliative chemotherapy was initiated. Two months following diagnosis the owner reported that the dog was doing well. This is the first report of a trigeminal nerve sheath tumour diagnosed via biopsy of the infraorbital nerve in a dog. Consideration should be given to evaluating the infraorbital nerve on clinical examination as well as MRI in cases of trigeminal neuropathy.

  • trigeminal neuropathy
  • cranial nerve
  • neoplasia
  • brain
  • peripheral nerve
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  • Contributors All authors were involved in the work-up, investigation, interpretation of diagnostic test results and write-up of this study.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement All data relevant to the study are included in the article.

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