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Cats
Computed tomographic findings in a case of feline insulinoma
  1. Eimear Shorten1,
  2. Adam Swallow2,
  3. Katie Elizabeth McCallum3,
  4. Cornelia Holzhausen4,
  5. Katherine Hughes4 and
  6. Marie-Aude Genain5
  1. 1Veterinary Medicine, University College Dublin, Dublin, Ireland
  2. 2Internal Medicine, Cave Veterinary Specialists, Somerset, UK
  3. 3Veterinary Medicine, Cambridge Veterinary School, Cambridge, UK
  4. 4Veterinary Medicine, University of Cambridge, Cambridge, UK
  5. 5Department of Clinical Veterinary Medicine, University of Cambridge, Cambridge, UK
  1. Correspondence to Dr Eimear Shorten; eimear.shorten{at}ucdconnect.ie

Abstract

Insulinomas are functional insulin-secreting tumours of the beta cells of the pancreatic islets which are rare in cats. Clinical signs are a result of hypoglycaemia and include seizures, collapse, weakness, ataxia, disorientation, mental dullness and visual disturbances. An 11-year-old male neutered domestic shorthair cat was presented with a history of having a single abnormal neurological episode. Persistent hypoglycaemia, hyperinsulinaemia and the presence of a well-defined pancreatic nodule on abdominal ultrasound resulted in a suspected diagnosis of insulinoma. Multiphasic CT angiography revealed a well-defined, homogeneous pancreatic mass which was isoattenuating to pancreatic parenchyma on precontrast images, had marked contrast enhancement in the arterial phase and moderate enhancement in the venous phase. CT angiography was a useful imaging modality for evaluating this case of histologically confirmed malignant insulinoma and its associated metastases.

  • oncology
  • pancreas
  • computed tomography (CT)
  • diagnostic imaging
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Footnotes

  • Contributors All authors made substantial contributions. AS and KEC managed the case. MAG was responsible for image acquisition and interpretation. CH and KH performed the histological evaluation and provided the histological figure. ES drafted the manuscript and provided the diagnostic imaging figures. All authors participated in critically appraising the manuscript and revising it for intellectual content. All authors gave final approval of the completed manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement All data relevant to the study are included in the article.

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