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Cats
Collagenofibrotic glomerulopathy in a young cat
  1. Monika Hilbe1,
  2. Manuela Schnyder2,
  3. Udo Hetzel1,
  4. Carole Schuppisser3 and
  5. Nicole Borel1
  1. 1Institute of Veterinary Pathology, Universitat Zurich Vetsuisse-Fakultat, Zurich, Switzerland
  2. 2Institute of Parasitology, Universitat Zurich Vetsuisse-Fakultat, Zurich, Switzerland
  3. 3Clinic for Small Animal Internal Medicine, Universitat Zurich Vetsuisse-Fakultat, Zurich, Switzerland
  1. Correspondence to Dr Monika Hilbe; hilbe{at}vetpath.uzh.ch

Abstract

Collagenofibrotic glomerulopathy, also named collagen III glomerulopathy, is a rare glomerulopathy type caused by deposition of collagen III in the glomerular mesangium and subendothelial space. The aetiology of this entity is unknown and the pathological mechanism remains poorly understood. It is mostly seen in humans in Asian countries, especially in Japan. Collagenofibrotic glomerulopathy has been described in a macaque, in dogs, pigs and in a cat, published as renal glomerular fibrosis. Here, the authors present a case of collagenofibrotic glomerulopathy in a young European domestic shorthair cat, which developed a severe hypoproteinaemia, hypoalbuminaemia and proteinuria and showed a concurrent natural non-patent infection with the canid lungworm Angiostrongylus vasorum.

  • cats
  • kidneys
  • pathology
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Footnotes

  • Contributors MH and NB, which did the autopsy, were both in charge of the interpretation of the histology and special stains as well as writing of the paper. CS did the clinical examination and gathered clinical data of the cat before euthanasia. UH was in charge of the TEM pictures and interpretation as well as correction of the paper. MS did the parasitological examination and corrected also this paper.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement All data relevant to the study are included in the article.

  • Author note The article "Collagenofibrotic glomerulopathy in a young cat" published in the Journal Veterinary Record Case Reports highlights the kidney problem and not the natural infection with the canid heart worm Angiosrongylus vasorum as published in Veterinary Parasitology: Regional Studies and Reports in 2019 and therefore describes another aspect of the cat's multifactorial health problem.

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