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Sheep and goats
Congenital intradural melanoma surrounding the spinal cord of a nine-day-old Saanen goat
  1. Devinn M Sinnott1,
  2. Kevin D Woolard2,
  3. Meera Heller3 and
  4. Verena K Affolter2
  1. 1William R Pritchard Veterinary Medical Teaching Hospital, University of California Davis, Davis, California, USA
  2. 2Department of Pathology, Microbiology, and Immunology, University of California Davis, Davis, California, USA
  3. 3Department of Medicine and Epidemiology, University of California Davis, Davis, California, USA
  1. Correspondence to Dr Devinn M Sinnott; dmsinnott{at}ucdavis.edu

Abstract

A nine-day-old Saanen kid presented for progressive hind limb paresis since birth. Euthanasia was elected, and on postmortem examination a large, pigmented mass was present in the vertebral canal surrounding the lumbosacral and caudal thoracic spinal cord. Histopathology revealed a homogeneous population of round to spindle neoplastic cells containing finely granular pigment consistent with a melanoma. This diagnosis was further supported by a Fontana-Masson stain and immunohistochemistry for PNL2, MelanA and SOX10. The tumour presumably arose from melanocytes or melanocytic precursors within the meninges of the lumbosacral spinal cord. No evidence of neoplasia was seen elsewhere in the body; therefore, the meningeal melanoma likely represents the primary tumour. Goats develop neoplasms less frequently than other species, and reports of congenital tumours in goats are rare.

  • neoplasia
  • goats
  • histopathology
  • central nervous system (CNS)
  • neonatal disease
  • pathology
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Footnotes

  • Contributors MH performed the antemortem clinical evaluation and euthanasia of the patient. DMS, VKA and KDW performed the postmortem gross evaluation and histopathological evaluation of the case.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement All data relevant to the study are included in the article.

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