Article Text

Download PDFPDF
Dogs
Antibodies to Leishmania infantum in peritoneal effusion from a dog with atypical signs of leishmaniosis: treatment and follow-up
  1. Sergio Villanueva-Saz1,
  2. Cristina Peréz Sala2,
  3. Andrés Yzuel Estévez3,
  4. Antonio Fernández4 and
  5. María Teresa Verde4
  1. 1Pharmacology and Physiology Department and Clinical Immunology Laboratory, University of Zaragoza, Zaragoza, Aragón, Spain
  2. 2Veterinary Teaching Hospital, University of Zaragoza, Zaragoza, Aragón, Spain
  3. 3Clinical Immunology Laboratory, University of Zaragoza, Zaragoza, Spain
  4. 4Animal Pathology Department and Clinical Immunology Laboratory, University of Zaragoza, Zaragoza, Aragón, Spain
  1. Correspondence to Dr Sergio Villanueva-Saz; svs{at}unizar.es

Abstract

A three-year-old entire male French bulldog was brought in with the following clinical signs: apathy, vomiting and abdominal distension. Physical examination showed dehydration, tachypnoea and presence of jaundice. Abdominal radiology revealed the presence of an important loss of details in the abdominal structures compatible with peritoneal effusion, confirmed by abdominal ultrasonography. Findings detected by ultrasonography consisted of splenomegaly with alteration of the echotexture, hepatomegaly with presence of nodules and irregular areas in the liver capsule. An ultrasound-guided sample of the peritoneal fluid was taken for laboratory analysis. Abnormal clinicopathological results included pancytopenia, hyperglobulinaemia, hypoalbuminaemia, and elevation of the hepatic parameters and total bilirubin. High antibodies to Leishmania infantum were detected by ELISA in serum and peritoneal fluid samples. However, PCR for L infantum showed a negative result from the peritoneal fluid sample. This is the first reported case of canine leishmaniosis with the specific detection of L infantum antibodies in peritoneal effusion.

  • leishmaniasis
  • dogs
  • hepatic disease
  • treatment
View Full Text

Statistics from Altmetric.com

Footnotes

  • Contributors All authors contributed to manuscript preparation. CPS, MTV and SVS carried out the veterinary examination, applied the treatments and followed up. SVS and CPS created the manuscript, which was edited by AYE, AF and MTV. All authors read and approved the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement All data relevant to the study are included in the article.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.