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Primary tonsillar histiocytic sarcoma in two dogs
  1. Cesar Llanos1,
  2. Ana Lara2 and
  3. James Elliott3
  1. 1Willows Veterinary Centre and Referral Centre, Solihull, UK
  2. 2Royal Veterinary College, London, UK
  3. 3Department of Radiation Oncology, North Carolina State University, Raleigh, North Carolina, USA
  1. Correspondence to Dr James Elliott; jameselliott44{at}


An eight-year-old, female-spayed Golden Retriever was presented with a tonsillar mass, which was diagnosed as histiocytic sarcoma (HS), following tonsillectomy. Clinical staging revealed no regional lymph node or distant metastasis. Following adjuvant lomustine treatment, the patient remains alive with no evidence of tumour recurrence 18 months after diagnosis. Additionally, a five-year-old, male-entire Golden Retriever presented with an enlarged retropharyngeal lymph node was also diagnosed with HS. A primary tonsillar mass, extensive regional lymph node involvement and suspected early pulmonary metastasis were discovered following clinical staging. After a cytoreductive surgery and no adjuvant chemotherapy, the dog was euthanased two months following diagnosis with progressive distant metastasis. To the authors’ knowledge, this is the first report documenting primary tonsillar HS in the dog. This case report illustrates an excellent outcome of a dog with localised HS following surgery and adjuvant chemotherapy. However, prognosis remains guarded for dogs with disseminated disease, especially when chemotherapy is not used.

  • histiocytic sarcoma
  • canine
  • CCNU
  • tonsillar
  • cancer
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  • Contributors Conception and design: CL and JE Drafting and revising article: CL, JE and AL. Final approval of version published: CL, JE and AL.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement All data relevant to the study are included in the article.

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