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Isoflurane maintenance of neuroanaesthesia in two dogs with hydrocephalus and syringohydromyelia undergoing ventriculoperitoneal shunt surgery
  1. Friederike Pohlin1,2,3,
  2. Keagan John Boustead1,2,
  3. Justin Frederick Grace1,2 and
  4. Gareth Zeiler1,2
  1. 1Department of Companion Animal Clinical Studies, University of Pretoria, Onderstepoort, South Africa
  2. 2Anaesthesia and Critical Care Service, Valley Farm Animal Hospital, Pretoria, South Africa
  3. 3Research Institute of Wildlife Ecology, Department of Interdisciplinary Life Sciences, University of Veterinary Medicine Vienna, Vienna, Austria
  1. Correspondence to Dr Friederike Pohlin; friederike.pohlin{at}


A two-year-old spayed female great dane crossbreed dog and a three-year-old spayed female Yorkshire terrier were presented for surgical correction of hydrocephalus and syringohydromyelia. Obstruction of cerebrospinal fluid flow and associated increase in cerebrospinal fluid volume commonly result in an elevated intracranial pressure. During anaesthesia, maintaining an optimal balance between intracranial pressure and cerebral perfusion is crucial to avoid neuronal damage. Volatile anaesthetics are the most commonly used drugs for maintaining anaesthesia in veterinary practice but have the potential to cause an increase in intracranial pressure through vasodilation. This case series describes inhalational maintenance of neuroanaesthesia for ventriculoperitoneal shunt surgery with isoflurane. Interventions applied to manipulate the anaesthetic drug’s effects on intracranial pressure to maintain optimal cerebral perfusion are described.

  • anaesthesia
  • neurosurgery
  • dogs
  • neuropathology
  • central nervous system (CNS)
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  • Contributors All authors were involved with the anaesthetic management of one, or both, cases and contributed to the writing of the case report. All authors have approved the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement All data relevant to the study are included in the article.

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