Complete response (CR) | Disappearance of all target lesions; pathological lymph nodes <10 mm short axis |

Partial response (PR) | ≥30% decrease in sum diameters of target lesions, taking as reference the baseline sum |

Stable disease (SD) | <30% reduction (PR) or 20% increase (PD) in the sum diameters of target lesions, taking as reference the smallest sum of diameters while on study |

Progressive disease (PD) | ≥20% increase in sum diameter of target lesions taking as reference the smallest sum of diameters while on study; the sum increase must be ≥5 mm, OR the appearance of one or more new lesions |